Neoprene boots have a zippered closure, velcro zipper keeper, and tend to be more flexible which allows a thicker than normal sock to be worn without cramping the foot.
The waterproof boots typically have a lace-up closure, are more rigid, and hold moisture just as well as it keeps the water out.
|Waterproof Boots||Rubber||Rigid||Tie up||Spring/Summer|
|Neoprene Boots||Neoprene||Flexible||Zipper||Year Round, Good for Winter|
Now lets take a look: